Would you recommend definitive XRT with extensive lymph node involvement of prostate cancer?
Is there an extent of nodal involvement in prostate cancer above which you would not offer definitive XRT? With PSMA/PET we see some patients with increased pelvic nodal disease. Alternatively, do you manage similar to STAMPEDE and treat with prostate directed therapy alone with hormone therapy/abiraterone?
1 Answer
Mednet MemberInvited Expert
Radiation Oncology
Answered on
In cases of lymph node positive disease, I favor RT to the prostate and lymph nodes (with long termADT ± abiraterone) if I believe all the gross disease can be encompassed in a tolerable radiation treatment plan. In STAMPEDE, RT was mandated in all N0 cases and encouraged in N+ cases, which resulted...
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