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Would you recommend hypofractionation in breast cancer patients who had partial mastectomy with significant oncoplasty?

1 Answer
Mednet MemberInvited Expert
Radiation Oncology · Mayo Clinic, Rochester, MN
Answered on

In the absence of robust data suggesting that use of oncoplasty should alter whole breast radiotherapy recommendations, hypofractionation is our preferred approach following partial mastectomy with oncoplasty in patients without indications for regional nodal irradiation. According to 10-year follow-up from START-B one may reasonably expect less late adverse events (i.e. less breast shrinkage, breast induration, breast edema, and telangiectasia) with 40 Gy in 15 fractions +/- a boost to the lump...

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