Would you recommend pre-op radiation for an operable recurrent well differentiated retroperitoneal liposarcoma with abutment of the right kidney?

Thank you for this question.

Per the STRASS trial (Bonvalot S, Gronchi A, Le Pechoux C, et al. Journal of Clinical Oncology 37, no. 15_suppl (May 20, 2019) 11001-11001), preoperative radiation overall did not impact abdominal recurrence free survival. However, in the exploratory analysis, the lipos...

Yes.

For recurrent well differentiated liposarcoma we would consider preoperative radiation therapy. We generally wait 6-8 weeks and then resect which would include a nephrectomy.

Based on Strass 1: STRASS failed to demonstrate a benefit of pre-operative RT for RPS. In the exploratory analysis, pre...

At Mayo Clinic Rochester and Mayo Clinic Arizona, preoperative irradiation followed by restaging, gross total resection (including the kidney in the above patient) and IORT to narrow or microscopically positive margins with electrons or HDR brachytherapy was the preferred approach for patients with ...

Yes