Would you recommend radiotherapy for upper-tract urothelial carcinoma in an inoperable patient?

Unfortunately, there are no good data to guide a decision in this circumstance. Assuming that this is a patient with a small tumor localized to the upper tract with no evidence of nodal or distant disease, radiotherapy might be a reasonable option to either palliate symptoms due to obstruction or bl...

I am hardly an expert on the topic, but have performed SBRT in this scenario. I found this paper very helpful for treatment planning.

Echoing others, there's limited data out there. I have treated several of these both for palliation and for 'ablation' in the setting of limited disease. Notably, UTUC often recurs elsewhere in the tract (e.g., I just saw a guy 2 years out with a new ureter lesion >4 cm from the site I gave SBRT).

G...

Yes, UTUC is dangerous especially high grade and older. Many aren't RUN candidates. Invasion is not easy to determine. There is data on SBRT along the upper tract. Topical mitomycin gel isnt the answer.
Evans et al., PMID 29556581, Khriguian et al., PMID 34530170

Also, if you treat a lot of primary re...