Would you recommend reirradiation in a patient who has extensive subcutaneous chest wall nodules and axillary recurrence after previous PMRT?

These are very difficult clinical situations that have nuances that make it hard to give a definitive answer. I would first ask what the status is of any distant disease, and if systemic therapy options have been exhausted. If this is localized disease, if it is symptomatic or about to be, if perfor...