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Would you recommend SBRT in the adjuvant settings for a solitary metastasis focus in the abdominal wall resected to R1 in a young and healthy patient with clear cell ovarian cancer?

5 Answers
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Radiation Oncology · University of Kentucky Albert B. Chandler Hospital

If it is truly an R1 resection, I would observe and follow with close imaging.

If she recurs, I would recommend a discussion for systemic therapy. If she has persistent disease that is amendable to SBRT, it is reasonable to treat. SBRT can prolong a chemotherapy holiday and dosing in the pelvis is us...

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Radiation Oncology · Allegheny Health Network

That depends on the systemic disease status, platinum eligibility, and prior radiation as well as proximity to nearby bowel. 90% of insurers won't cover SBRT without very compelling reasons to (prior disease, no systemic options remaining, etc etc) so outside of a few select institutions, in most pl...

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Radiation Oncology · Sylvester Comprehensive Cancer Center

This would be reasonable to proceed with observation. If this is recurrent disease, I would do systemic and close monitoring and treat if suspected recurrence.

I don’t think strictly wrong either though to treat if the target is clear, and no luminal GI nearby.

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Radiation Oncology · Vanderbilt-Ingram Cancer Center

Would not treat with adjuvant RT in what is presumably a port-site metastasis. If the patient recurs in a limited fashion, treat at the time of gross disease.

Whether the patient requires systemic therapy now (versus at the time of future recurrence) would be worth a discussion. I would personally f...

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Radiation Oncology · Sunnybrook Health Sciences Centre

I am not aware of any evidence to recommend adjuvant SBRT and I would not treat this patient even if R1 resection, what I presume is a port site recurrence.

The patient's systemic options need to be considered in this case if any. If ok to be not on any systemic therapy, then I would recommend obse...

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Would you recommend SBRT in the adjuvant settings for a solitary metastasis focus in the abdominal wall resected to R1 in a young and healthy patient with clear cell ovarian cancer? | Mednet