Topics:
Head and Neck Cancers • Medical Oncology
Would you recommend the addition of chemotherapy in a patient with locally recurrent, unresectable squamous cell carcinoma of the head and neck for whom repeat radiation is planned?
Patient received full dose concurrent cis + RT previously.
Answer from: Medical Oncologist at Academic Institution
There is no standard of care in the setting of an unresectable, resistant local/regional recurrence after full dose RT and concurrent cisplatin. If the patient has a good PS, is medically fit, and the goal is a salvage cure, I would discuss adding a taxane to the planned RT. In an attempt to overcom...
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Answer from: Medical Oncologist at Academic Institution
This is a very challenging question in the setting of no solid guidelines. Enrollment in clinical trials, if available, would be highly recommended. Otherwise, decision to use a radiosensitizer agent in this space has to be in a multi-D setting discussion with a radiation oncologist who is very fami...