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Would you require biopsy of both orbits or is unilateral biopsy adequate for a patient with suspected bilateral orbital MALT lymphoma?

Imaging studies (MRI and PET) show bilateral disease
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Would you perform biopsies of both orbits for a patient with suspected bilateral orbital MALT lymphoma?

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2 Answers
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Radiation Oncology · Duke University Medical Center
Answered on

Biopsy of one orbit is sufficient if clinical findings and images of the other orbit are all consistent with marginal zone lymphoma (MZL). I’m a little surprised the question of how to treat bilateral MZL of orbit was not asked. Assuming disease is limited to the orbits, radiotherapy to both sites w...

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Mednet Member
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Radiation Oncology · Varian Medical Systems/Allegheny health network
Answered on

If imaging is concordant on both sides then would favor only one biopsy to confirm pathology.

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