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Would you transition from IV to oral antibiotics in a solid organ transplant recipient with uncomplicated gram-negative bacteremia?

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Do you routinely transition from IV to oral antibiotics in a solid organ transplant recipient with uncomplicated gram-negative bacteremia?

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1 Answer
Mednet Member
Mednet MemberInvited Expert
Infectious Disease · Johns Hopkins University
Answered on

Yes, I would in the right circumstances. The referenced article by Nussbaum et al., PMID 38195100 provides reasonable evidence that this is a valid approach. Particularly, if the patient's net-state-of-immunosuppression is not terribly high and the organism is susceptible to highly bioavailable oral...

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