Would you treat a T2N0 high grade neuroendocrine carcinoma of the nasal cavity after a R1 resection?

Factors such as PNI or LVI are important to consider.

In my practice, I always treat these patients. Nasal cavity resections are usually endoscopic resections that result in positive or close margin so adjuvant therapy is usually needed.

High grade neuroendocrine cancers have high risk of local rec...