Topics:
Lung Cancer • Radiation Oncology • Neuro-Oncology • Thoracic Malignancies • Medical Oncology • Small cell lung cancer • SWOG
Would you use a hippocampal sparing technique when treating with PCI for a limited stage small cell lung cancer?
Answer from: Radiation Oncologist at Academic Institution
This is an important question where the evidence is evolving, and some key trials remain ongoing. Because the data remains in flux, in the ongoing phase 3 SWOG S1827/Maverick trial of MRI surveillance +/- prophylactic cranial irradiation (PCI) for LS and ES-SCLC, where I serve as the PI, hippocampal...
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Answer from: Radiation Oncologist at Community Practice
The potential cognitive preservation benefits of hippocampal sparing remain the subject of ongoing phase III trials. In the setting of PCI for small cell lung cancer, NRG CC003 is a phase III trial of PCI with or without hippocampal avoidance; at our institution, eligible patients are enrolled...