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Would you use a triptan in a patient with a vascular malformation, such as an arteriovenous malformation, cavernous malformation, or developmental venous anomaly?

Typically, a gepant would be used, but this is inaccessible to most Medicare patients where I practice. Is there any evidence regarding the safety of triptan use in this population?
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Do you use triptans in the patients with vascular malformations?

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2 Answers
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Neurology · Greater Boston Headache Center at Boston Advanced Medicine
Answered on · Updated on

I see no reason not to use a triptan under the circumstances mentioned. I consider the gepants indicated when there are contraindications to the triptans, which are: poorly or uncontrolled hypertension and (atherosclerotic) vascular disease affecting the heart, brain, bowel, or legs. The above-menti...

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Mednet Member
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Neurology · UPMC
Answered on

I am not aware of any evidence to support withholding the use of triptans as abortive treatment in cases with these vascular malformations. I have routinely used triptans as abortive treatment in these patient populations.

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