How do you counsel families of prepubertal girls with an oncologic diagnosis about cryopreservation of ovarian tissue?

One of the biggest current issues with ovarian cryopreservation (OTC) in the US is that there is no consensus yet about who should receive OTC, and practice varies across the country. In addition, many patients are diagnosed and treated at centers that do not have oncofertility programs and do not offer OTC. So, there are significant variations in practice across the country.

At Phoenix Children's Hospital, we only offer OTC to the highest-risk females. Our current criteria are:

1. Females >6 mo...