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After a course of treatment for neurosyphilis, do you administer an additional IM dose of penicillin G one week after finishing the course of IV penicillin therapy?

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For ID specialists and others with considerable experience managing syphilis: Do you advise a dose or two of benzathine penicillin G following IV penicillin for neurosyphilis?

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1 Answer
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Infectious Disease · University of Washington Center for AIDS and STD
Answered on · Updated on

Excellent question. This has been the topic of a never-ending (if somewhat behind-the-scenes) debate among syphilis experts for decades. In fact, it came up for discussion just a few days ago after a presentation on syphilis at IDWeek in Boston, the Infectious Disease Society of America's annual con...

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