Are there any circumstances in which you would recommend adjuvant chemoradiation for resected olfactory neuroblastoma?

Agree with Dr. @Dr. First Last. Our experience treating 29 patients with Kadish B and C neuro esthesioneuroblastoma with local RT if positive margins, and no neck RT when the neck was N0, resulted in 27% neck failure including in the contralateral neck. 5-year LRF rate was 29% in patients who did no...

Nearly all. I can’t recall one I haven’t treated. And always include ENI.

I'd typically offer radiation to patients with large intracranial extension, Kadesh C disease. It's rare.

Agree with post op RT and neck ENI recs per above. Unlike the more undifferentiated versions like SNUC or Small cell, there is no routine role for chemo for a pure Esthesio NB. @Dr. First Last and @Dr. First Last from MDACC published on this, see PMID 15517582.