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Can you use Mammaprint to decide on chemotherapy in a young patient with positive sentinel nodes if no further axillary dissection is planned to see if there is more nodal involvement?

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Medical Oncology · Baptist Health South Florida
Answered on

Mammoprint is the only genomic assay with level one evidence in node positive patients. Assuming that no axillary dissection to be done suggests ACOSOG Z-11 in a lumpectomy patient. Most would agree that taking more than one sentinel node decreases the risk of false negative assays so, in a patient like this it would have been preferable if more than one sentinel node was taken. Also, no info given on other prognostic variables to establish a clinical risk pattern of the primary. With those prov...

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