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Dermatology

Dermatopathology   

Questions discussed in this category

What is your preferred stain for melanocytic lesions?
SOX-10, MITF, PRAME, S100, etc? 
1 Answer available
Do you recommend an additional procedure for melanomas if there is tumor within 1-2mm of the margin?
3 Answers available
What histologic findings most commonly lead you to order additional staining for potential desmoplastic melanoma?
Especially in cases where the MIS portion is obvious but the dermal component may not be.
1 Answer available
What is your approach to the use of intravenous sodium thiosulfate for the management of calciphylaxis in a patient with end stage kidney disease and on hemodialysis?
1 Answer available
How do you utilize PRAME for melanocytic biopsies?
Do you use it for excisions to determine if margins are clear? Do you use it for all melanocytic biopsies? How do you balance using PRAME with the...
1 Answer available
Do you recommend a deep shave biopsy or punch biopsy for sampling concerning melanocytic lesions?
3 Answers available
What clinical or pathologic features would make you more concerned that a new skin SCC is from metastatic disease or a new cutaneous primary?
1 Answer available
When do you order genetic studies such as comparative genomic hybridization for melanocytic lesions?
1 Answer available
What are your preferred IHC stain(s) for desmoplastic melanoma?
1 Answer available
What IHC stains do you routinely use for identifying invasive squamous cell carcinomas?
1 Answer available
How do you differentiate atopic dermatitis from mycosis fungoides histologically?
1 Answer available


Papers discussed in this category

Journal of the American College of Surgeons, 2011-04
Shave biopsy is a safe and accurate method for the initial evaluation of melanoma.
Am J Surg,
Effect of biopsy type on outcomes in the treatment of primary cutaneous melanoma.
The American Journal of dermatopathology, 2013-07
SOX10 expression distinguishes desmoplastic melanoma from its histologic mimics.
The American journal of surgical pathology, 2018-03
Distinguishing Neurofibroma From Desmoplastic Melanoma: The Value of p53.
The American journal of surgical pathology, 2018-11
PRAME Expression in Melanocytic Tumors.
Appl Immunohistochem Mol Morphol,
SOX10 expression in malignant melanoma, carcinoma, and normal tissues.
Pathology, 2016 Aug 28
SOX10 expression in cutaneous scars: a potential diagnostic pitfall in the evaluation of melanoma re-excision specimens.
Am J Dermatopathol,
Sox10-Positive Cells Within Scars: A Potential Diagnostic Pitfall.
Am J Dermatopathol,
SOX-10 and S100 Negative Desmoplastic Melanoma: Apropos a Diagnostically Challenging Case.
Mod Pathol, 2020 Feb 17
DNA copy number changes correlate with clinical behavior in melanocytic neoplasms: proposal of an algorithmic approach.

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