Endocrinology

Electrolyte disorders

Questions discussed in this category

Do you interpret failure to develop hypernatremia with prolonged water deprivation (such as for 12 hours) as evidence against diabetes insipidus even if the urine osmolality is just below normal?

For a patient whose sodium remains 142 despite water deprivation from 8 pm to 8 am, with urine osm of about 500, is further testing needed?

2 Answers available

What strategies do you use to prevent overcorrection of serum sodium in patients with severe hyponatremia and adrenal insufficiency when initiating glucocorticoid therapy?

1 Answer available

What is your approach to differentiating diabetes insipidus from primary polydipsia in the outpatient setting?

1 Answer available

Has your management of severe hyponatremia changed after a recent observational study described higher in-hospital mortality for sodium correction of <6 mEq/L compared to 6-10 mEq/L in the first 24 hours?

Seethapathy et al., NEJM

5 Answers available

In SIADH due to malignancy, do you prefer to use free water restriction or salt tablets?

Or other therapy - e.g., tolvaptan? Free water restriction may hinder QOL. Salt tablets may raise levels more quickly but have risks of edema and hype...

1 Answer available

Do you routinely use 3% sodium chloride and desmopressin to correct hypovolemic hyponatremia in an asymptomatic patient with serum sodium of less than 120 mEq/L?

3 Answers available

What is your daily correction goal for those patients being treated for hypernatremia?

2 Answers available

How do you approach a patient with biochemical evidence of primary hyperparathyroidism, but normal parathyroid scan?

4 Answers available

What is your approach to using bisphosphonates in those with severe hypercalcemia and chronic kidney disease?

1 Answer available

Does your goal rate of correction in patients with chronic hypoosmolar hyponatremia differ based on the degree of hypoosmolarity?

4 Answers available

Do you recommend stopping Vitamin D supplementation in a patient with hypercalcemia and a low 25(OH)D level?

1 Answer available

What is your approach to managing hypocalcemia following a parathyroidectomy in patients with end stage kidney disease?

1 Answer available

Papers discussed in this category

Clinical journal of the American Society of Nephrology : CJASN, 2019-05-07

Rate of Correction of Hypernatremia and Health Outcomes in Critically Ill Patients.

Curr Opin Cell Biol, 1995 Aug

Cell volume regulated transporters of compatible osmolytes.

The American journal of medicine, 2016-05

Diagnosing and Treating the Syndrome of Inappropriate Antidiuretic Hormone Secretion.

Clinical journal of the American Society of Nephrology : CJASN, 2018-07-06

Risk Factors and Outcomes of Rapid Correction of Severe Hyponatremia.

Journal of critical care, 2023 May 13

Effects of correction rate for severe hyponatremia in the intensive care unit on patient outcomes.

The Journal of urology, 1992-06

Functional obstructive uropathy: a significant factor in the hyponatremia of psychogenic polydipsia?

American journal of kidney diseases : the official journal of the National Kidney Foundation, 2013-04

Hypertonic saline and desmopressin: a simple strategy for safe correction of severe hyponatremia.

Endocrinology

Electrolyte disorders

Questions discussed in this category

Papers discussed in this category

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