Infectious Disease

Neuro-infectious disease

Questions discussed in this category

How do you balance the risk of unnecessary treatment with acyclovir against the risk of delaying treatment in encephalitis cases where CSF pleocytosis is absent?

Habis et al., PMID 39096271

1 Answer available

What antibiotics would you use for empiric treatment of a brain abscess in patients allergic to penicillin, metronidazole, and vancomycin?

1 Answer available

What are the current treatment options for progressive multifocal leukoencephalopathy in patients without HIV/AIDS?

Are there any clinical trials underway to study additional therapies?

1 Answer available

Do you choose an antibiotic with CSF penetration, such as nafcillin over cefazolin, in the setting of MSSA endocarditis with septic emboli to the brain (assuming no concomitant meningitis or brain abscess)?

3 Answers available

Do you repeat a lumbar puncture in a patient living with HIV diagnosed with and treated for neurosyphilis and if so, when?

1 Answer available

What is your approach to the treatment of PML-IRIS in patients with HIV who have progressed to AIDS?

1 Answer available

When would you consider checking JC virus prior to initiating biologic therapy?

1 Answer available

Papers discussed in this category

Journal of neurovirology, 2018-06

Progressive multifocal leukoencephalopathy in rituximab-treated rheumatic diseases: a rare event.

The Journal of infectious diseases, 1980 Mar

A study of cephalothin and desacetylcephalothin in cerebrospinal fluid in therapy for experimental pneumococcal meningitis.

Antimicrobial agents and chemotherapy, 1976 Sep

Pharmacological study of cefazolin during intermittent and continuous infusion: a crossover investigation in humans.

Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases, 2020 May 08

Should we reconsider cefazolin for treating staphylococcal meningitis? A retrospective analysis of cefazolin and cloxacillin cerebrospinal fluid levels in patients treated for staphylococcal meningitis.

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