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Rheumatology

DMARD   

Questions discussed in this category

Do you combine methotrexate and leflunomide for the treatment of RA?
3 Answers available
What is your preferred add-on for membranous lupus nephritis (2.2 grams of protein, normal creatinine) in a young woman who is currently on hydroxychloroquine and mycophenolate 1500 mg 2x daily?
2 Answers available
How do you approach treatment of a patient with active RA and a history of Lynch Syndrome?
Does your choice of DMARD/biologics change due to increased risk of malignancy?
1 Answer available
Do you feel comfortable combining mycophenolate mofetil with azathioprine in patients with lupus?
3 Answers available
What is your approach to transitioning an SLE patient from a pregnancy incompatible regimen to pregnancy compatible regimen?
For example, when switching from MMF to azathioprine, do you overlap the treatments as you lower the dose of one and add the other?
3 Answers available
How often do you monitor labs in patients taking methotrexate?
4 Answers available
Do you use conventional DMARDs aside from methotrexate to prevent anti-drug antibody development for patients on infliximab?
This question is part of a collaboration with RheumMadness and is specifically in reference to: Etanercept + Methotrexate.
3 Answers available
How do you counsel patients regarding alcohol intake when prescribing DMARDs other than methotrexate?
Such as Leflunomide, Sulfasalazine, Mycophenolate or Azathioprine, since all of these medications have potential to cause liver enzyme elevation and i...
1 Answer available
How long do you expect gastrointestinal side effects of leflunomide to persist after stopping treatment?
2 Answers available
How do you manage nausea in the setting of hydroxychloroquine use?
1 Answer available
Which medications have the lowest risk of tuberculosis reactivation in patients with uncertain tuberculosis history and active rheumatologic disease?
2 Answers available
How do you approach DMARD therapy in a patient with lupus and recurrent pericarditis?
1 Answer available


Papers discussed in this category

Lupus, 2013-07
Erythrocyte sedimentation rate is a predictor of renal and overall SLE disease activity.
Arthritis care & research, 2019-07
Area-Level Predictors of Medication Nonadherence Among US Medicaid Beneficiaries With Lupus: A Multilevel Study.
Arthritis care & research, 2019-11
Azathioprine and Mycophenolate Mofetil Adherence Patterns and Predictors Among Medicaid Beneficiaries With Systemic Lupus Erythematosus.
Rev Med Interne, 2016 Oct 13
[Blood concentration of hydroxychloroquine in systemic lupus erythematosus care: Usefulness and limits].
JAMA Dermatol,
Hydroxychloroquine-induced pigmentation in patients with systemic lupus erythematosus: a case-control study.
Ann Rheum Dis, 2014 Apr 16
Treat-to-target in systemic lupus erythematosus: recommendations from an international task force.
J Rheumatol,
Flares in lupus: Outcome Assessment Trial (FLOAT), a comparison between oral methylprednisolone and intramuscular triamcinolone.
Lupus Sci Med, 2018 May 14
Quantifying the burden of steroid-related damage in SLE in the Hopkins Lupus Cohort.
Lupus Sci Med,
Efficacy of belimumab in two serologically distinct high disease activity subgroups of patients with systemic lupus erythematosus: post-hoc analysis of data from the phase III programme.
Lupus, 2015 Jul 10
Colchicine: a simple and effective treatment for pericarditis in systemic lupus erythematosus? A report of 10 cases.
Support Care Cancer, 2019 Dec 13
Effects of ginger adjunct to the standard prophylaxis on reducing carboplatin and paclitaxel-induced nausea vomiting: a randomized controlled study.
BMJ, 2023 May 30
Risk stratified monitoring for methotrexate toxicity in immune mediated inflammatory diseases: prognostic model development and validation using primary care data from the UK.
BMJ, 2023 May 30
Monitoring methotrexate toxicity: Are we being over-vigilant?
Current opinion in rheumatology, 2014-03
Systemic lupus erythematosus and pregnancy outcomes: an update and review of the literature.
Rheumatology (Oxford, England), 2013 Feb 04
Low risk of renal flares and negative outcomes in women with lupus nephritis conceiving after switching from mycophenolate mofetil to azathioprine.
Arthritis Rheumatol, 2020 Aug 4
CALIBRATE: A Phase 2 Randomized Trial of Rituximab Plus Cyclophosphamide Followed by Belimumab for the Treatment of Lupus Nephritis.
Trials, 2022 Nov 12
Efficacy of belimumab combined with rituximab in severe systemic lupus erythematosus: study protocol for the phase 3, multicenter, randomized, open-label Synbiose 2 trial.
Annals of internal medicine, 2021 Oct 26
Effectiveness of Belimumab After Rituximab in Systemic Lupus Erythematosus : A Randomized Controlled Trial.
Arthritis care & research, 2019 Jun
The Impact of Belimumab and Rituximab on Health-Related Quality of Life in Patients With Systemic Lupus Erythematosus.
BMC public health, 2008 Jan 21
The SMILE study: a study of medical information and lifestyles in Eindhoven, the rationale and contents of a large prospective dynamic cohort study.

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