Interstitial lung disease   

Questions discussed in this category



Given poor pulmonary outcomes in people with anti-PL12 antibodies, would you recommend more aggressive therapy? The patient was diagnosed with onset o...

Patients on baseline mycophenolate and azathioprine were excluded from the INBUILD trial however many patients with CTD-ILD will be on some form of im...

Do you base the decision on FEV1, 6MWD or symptoms at initial evaluation, or progression over time?

When adding nintedanib what sort of treatment course do you counsel the patient on? Do you plan to continue it indefinitely as long as the patient tol...

Do you prefer to start with nintedanib and then add immunosuppressive agents, or give a trial of immunosuppressive medication first, then add nintedan...

How is your approach to treatment different than other ILD patterns such as NSIP? Does treatment response vary based on underlying CTD?

Cyclophosphamide/tacrolimus and Rituximab have been used in conjunction with steroids in case series.

The SENSCIS trial was published in 2019 on efficacy of this agent. However, it's not clear where this should be in the treatment algorithm: Monot...


Papers discussed in this category


N. Engl. J. Med., 2019 May 20

The Lancet. Respiratory medicine, 2016-09

The New England journal of medicine, 2006-06-22

Archives of internal medicine, 2008-09-22

Arthritis and rheumatism, 2010-06

N Engl J Med,

Nature reviews. Rheumatology, 2018-05

Lancet Respir Med, 2020 Aug 28

Trials, 2017 Jun 15

N Engl J Med, 2019 Sep 29

N Engl J Med, 2012 May 20

J Heart Lung Transplant, 2021 Nov

Interact Cardiovasc Thorac Surg, 2015 Jan 07

Rheumatology (Oxford, England), 2011 Dec 30

Arthritis Rheum,

The European respiratory journal, 2015-10

The European respiratory journal, 2019-01

Eur Respir J, 2019 Jan 24

Eur Respir J, 2019 Jan 24

Arthritis & rheumatology (Hoboken, N.J.), 2017-03

Lancet Respir Med, 2021 Jan

Journal of clinical rheumatology : practical reports on rheumatic & musculoskeletal diseases, 2022 Jun 11

European respiratory review : an official journal of the European Respiratory Society, 2021 Dec 22

Clin Med Insights Circ Respir Pulm Med, 2021 Mar 30

Cureus, 2022 Sep 06

Respir Res, 2023 Jan 9

Cancer Treat Rev, 2022 Mar 12

Lancet Respir Med, 2023 Jan