Neurology
Expert perspectives on neurological conditions, stroke management, movement disorders, and neuromuscular disease.
Recent Discussions
When do you consider cardiac CT to evaluate for etiology of acute ischemic stroke?
I do it in place of TEE in: Patients with LVO or severe stenosis, for whom I am concerned about hypoperfusion causing another stroke. Elderly patients that may have a higher complication risk from TEE. I am mainly looking for intracardiac thrombus.
When do you use anticoagulation over antiplatelet therapy for secondary stroke prevention in patients with LV injury or dysfunction?
First, I will observe that the recent work is a cohort study, not an RCT< and I would be careful about concluding that anticoagulation is the best approach. We have had prior trials, e.g., WARCEF and the related ESUS trials (NAVIGATE and RESPECT), and others that have looked at possible cardioemboli...
What do you recommend to patients when they are having an acute flare of fibromyalgia symptoms?
Great, this is a really important area and unmet need in the field of fibromyalgia management. Unlike other nociplastic disease states (e.g., migraine), there are no rigorously studied abortive therapies to rapidly treat a flare of centralized pain. Indeed, all the therapies we use for FM are intend...
What resources do you find helpful for patients with MSK concerns who may not have access to physical therapy or who cannot afford it?
This is an excellent question and important because every MSK concern needs some form of exercise intervention for maximum benefit/recovery. In some (most?) EMR systems, general, basic home exercise programs (HEP) are available for patients. This is a convenient way to get patients started. Rarely, ...
Is it safe to use monthly injectable CGRP antagonists with oral gepants in the same patient?
Yes. To my knowledge, there is no data to suggest that it is not. I have routinely used oral gepants as abortive treatment in patients who are on a CGRP monoclonal antibody for prevention.There have been at least 2 retrospective studies looking at the safety and tolerability of using oral gepants in...
What is the utility of a hypercoagulability workup in recurrent cryptogenic stroke, and what specific tests would you recommend?
Ambulatory monitoring for AFib is probably more helpful than such a thorough clotting workup.
What traditional or herbal medications do you regularly screen for in migraine patients?
I do not particularly screen for any. I go over the medicine and supplement/vitamin list that they are taking. I counsel patients on the option of using OTC vitamins/supplements for migraine disorder prevention. I routinely counsel on magnesium 500 mg daily, riboflavin 400 mg daily, and coenzyme Q10...
What techniques do you use to help reduce procedural pain for headache injection treatments?
In my clinic, none of the providers, to my knowledge, use any specific techniques to reduce procedural pain. We do offer ice packs that patients can use during or after a procedure. We do Botox and pericranial nerve blocks. It would be difficult to coordinate using REN prior to procedures. I suppose...
How do you decide when to discontinue immunotherapy for primary angiitis of the central nervous system (PACNS)?
I take a multidisciplinary approach with involvement of my neurobiology and rheumatology colleagues for the immunotherapy. PACNS can be relapsing or remitting. So needs close monitoring with radiologic (MRI and MRA high resolution vessel wall imaging or CTA/MRA with CSF studies 6 months and then 1 y...
How can I incorporate neuromuscular ultrasound into my practice with limited prior experience?
I think it's awesome when anybody is willing to implement a new tool into their established clinical workflow. My suggestion, if you are already an EMGer, would be to start small and simple with a focus on upper extremity focal neuropathy and practice, practice, practice.Carpal tunnel syndrome and u...