Psychiatry
Expert discussions on psychopharmacology, behavioral health interventions, and psychiatric care approaches.
Recent Discussions
How do you manage sleep disturbances in patients with Alzheimer’s disease without relying heavily on deliriogenic medications?
Sleep disturbances are common in older people and in those with Alzheimer’s disease (AD) in particular, and there are often multiple etiologies. Whether sleep disturbances increase the risk for AD, or are a result, metanalyses have suggested that the magnitude of sleep impairment correlates with the...
Do you still consider changing atypical antipsychotics that are working well in children undergoing puberty if the prolactin levels are high but there are no symptoms of drug-induced hyperprolactinemia?
I consider the risk of osteoporosis if I believe it may be used long-term, even if asymptomatic. Typically, I warn parents of the risk but continue the medication if the prolactin is only mildly elevated. I find it rare to find an adult patient who is taking the same drugs they did in adolescence. L...
Do you believe that buspirone is ineffective in patients who are previously treated with benzodiazepines?
I've found buspirone helpful for patients who don't want to taper their benzo unless they have another medication on board. I wait until the buspirone is at a stable dose (typically at least 15 mg BID) before tapering the benzo. I specifically avoid cross-tapering/titration as I worry they will asso...
How do you counsel patients on lithium about NSAID use?
I recommend not using NSAIDs altogether, since there are so many variables to consider if the patient is to remain safe. The patient needs to be highly aware and knowledgeable about their medications, medical problems, age, baseline labs, etc. There are not very many patients like that.
What therapeutic approaches have you found effective for athletes with anorexia nervosa whose eating disorder symptoms are intertwined with sport-driven weight pressures?
The gold standard for treatment of anorexia nervosa and all eating disorders is a team-based approach, including the individual, psychiatrist, counselor, primary care or sports medicine physician, dietician, appropriate family members, and, in the case of elite athletes, sometimes their coaches. Rap...
How do you manage daytime somnolence without a clear cause?
I have a cohort of probably 5-10 patients now, mostly female in their late teens to early twenties, who report needing 10-14 hours of sleep per day and still not feeling refreshed. Excessive daytime somnolence (falling asleep in class or while driving). I tried modafinil and stimulants with modest s...
What work up do you pursue for a thorough evaluation in patients that present with a potential diagnosis of dermatitis artefacta?
I have found dermatologic complaints some of the most challenging in my psychiatric practice. Dermatitis artefacta (DA) occurs when an individual produces self-inflicted skin lesions in order to assume the sick role, making it a type of factious disorder. When evaluating a patient with suspected DA,...
What is your pharmacological approach to treating depressive disorders in patients who develop serotonin toxicity?
I would try bupropion. Not Auvelity, as dextromethorphan has serotonergic activity. I would want to see if they were on any medication other than psychiatric that contributed to serotonin syndrome, like tramadol, and get rid of that or replace it as needed. I would probably want to transition to a n...
When do you consider the use of N-acetylcysteine (NAC) in patients with trichotillomania?
Great question! NAC comes up frequently in clinical discussions of trichotillomania, and it's worth being clear-eyed about what we actually know. NAC restores extrasynaptic glutamate homeostasis via the cystine-glutamate antiporter (system Xc⁻), which increases tonic activation of presynaptic mGluR2...
How do you treat extrapyramidal symptoms secondary to anti-psychotic use in patients who have not benefited from cogentin or benadryl?
In general, when addressing motor symptoms from antipsychotics (or any dopamine-blocking agents including dopamine-blocking antiemetics), I find it useful to break things down more specifically than just EPS. This often will determine the agent that will be most beneficial. First Category: Hypokinet...