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Do you anticipate trying nemolizumab in patients with other difficult to treat pruritic conditions?

For example, there was recently a study in JAMA showing efficacy in cholestatic pruritis.
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Do you anticipate trying nemolizumab in patients with other difficult to treat pruritic conditions?

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2 Answers
Mednet Member
Mednet MemberInvited Expert
Dermatology · UCONN
Answered on

I have already used this drug in a multitude of off-label indications, including but not limited to lichen simplex chronicus, acne keloidalis nuchae, keloids secondary to acne fulminans, delusions of parasitosis, itch of unknown origin, nostalgia parasitic, scrotal pruritus, and occipital neuralgia.

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Mednet Member
Mednet Member
Dermatology · Washington University in St. Louis
Answered on

Absolutely. Nemolizumab has a uniquely anti-pruritic profile that seems to extend beyond traditional inflammatory pruritus.

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