Do you consider dermal invasion an indication for PMRT in the absence of other risk factors?

Did the patient have neoadjuvant chemotherapy between diagnosis and surgery?

If yes, than I would treat based on upfront clinical staging. If over 60 and no reconstruction would consider 40 Gy/15 fx to chest wall and nodes otherwise 50/25 fx or Alliance Trial if interested.

If no neoadjuvant che...

The limited data on non inflammatory breast ca with dermal lymphatic invasion suggest higher locoregional recurrence and I do offer PMRT

I wonder whether dermal lymphatic invasion is considered the same thing as invasion of the dermis? Based on the clinical description of peau d'orange, dermal invasion for this particular case may suggest tumor involvement of the dermal lymphatics which can be missed or difficult to identify on patho...

There is dermal lymphatic invasion and dermal lymphatic invasion. Do we treat patients with limited lymphovascular invasion and negative nodes if there are no other indicators? Probably not, based on subset analyses from multiple studies. However, refer to a recent Red Journal article on the amount ...