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Do you continue ovarian suppression for metastatic hormone-positive breast cancer patients who are premenopausal, regardless of line of therapy?
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Mednet Member
Medical Oncology · Warren Alpert Medical School of Brown University
I continue OFS while a patient is on an endocrine therapy, but discontinue OFS if the patient demonstrates resistance to endocrine therapies and transitions to chemotherapy, which typically suppresses ovarian function anyway.