Do you have safety concerns when prescribing GLP-1 medications in patients on corticosteroids or immunosuppressive therapy?

I think we need to be particularly careful when co-prescribing with systemic corticosteroids because of the risk of sarcopenia. We know that rapid weight loss is accompanied not only by a loss of fat tissue but also of muscle. Corticosteroids can also have myotoxicity and cause muscle atrophy. I the...

We do not have data that I am aware of regarding the safety of GLP-1 medications in this patient population. However, I am also not aware of any data indicating that GLP-1RA drugs would present a problem in patients receiving these medications. I would address this on a case-by-case basis, consideri...

I do not have specific safety concerns regarding the use of GLP-1 agonists in patients taking steroids or immunosuppressants, as I'm not aware of any data suggesting that these patients are at higher risk than anyone else.

No, I don't have any safety concerns, and this was kind of shown through the Together-PsA study. There were no different adverse events than those that would be seen with either drug alone. So no worries in prescribing both.