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Do you have safety concerns when prescribing GLP-1 medications in patients on corticosteroids or immunosuppressive therapy?

2 Answers
Mednet Member
Mednet Member
Rheumatology · Sorbonne Université

I think we need to be particularly careful when co-prescribing with systemic corticosteroids because of the risk of sarcopenia. We know that rapid weight loss is accompanied not only by a loss of fat tissue but also of muscle. Corticosteroids can also have myotoxicity and cause muscle atrophy. I the...

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Mednet Member
Mednet Member
Rheumatology · Northwestern University Feinberg School of Medicine

I do not have specific safety concerns regarding the use of GLP-1 agonists in patients taking steroids or immunosuppressants, as I'm not aware of any data suggesting that these patients are at higher risk than anyone else.

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