Do you recommend irradiating the remaining penis and pelvis vs pelvis alone in a patient with partial penectomy with negative margins who has multiple, positive groin nodes with ECE?

Generally agree with the comments by Dr. @Dr. First Last. The NCCN guidelines tend to recommend chemotherapy followed by node dissection without planned radiation. Post op XRT is reserved for certain situations (which is very toxic after groin dissection ). I have found that treating the penile stum...

Unfortunately, there aren’t any good clinical studies to define the optimal treatment in this scenario. Based on extrapolation from vulvar or H&N SCC treatment principles, adjuvant radiotherapy would be expected to improve at least the in-field control. In the situation of positive inguinal lymph no...