Do you routinely offer doxycycline or minocycline prophylaxis for cutaneous reactions to EGFR inhibitors such as cetuximab?

Topics: Head and Neck Cancers • Gastrointestinal Cancers • Medical Oncology • Colorectal Cancer • Supportive Care

If you do not use prophylaxis, what skin care strategy do you employ?

Answer from: Medical Oncologist at Academic Institution

When we use EGFR inhibitor for colorectal cancer, we routinely use the STEPP regimen that showed significant benefits in the phase II study including skin moisturizers, sunscreen, topic steroids, and doxycycline. In the phase II STEPP study, using this pre-emptive treatment significantly decreased s...

Comments

Medical Oncologist at University of Wisconsin
Dr. @Zhaohui Jin beat me to it. We use the ST...

Medical Oncologist at PeaceHealth
Not all patients develop cutaneous reactions to ce...

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