Do you think it makes a difference to fractionate at 2 Gy versus 1.8 Gy per fraction?

This is a great question and is an example of how a single clinical decision can change practice. In the era of radiation alone the standard fractionation was 2 Gy/day. With the introduction of concurrent chemoradiation the radiation dose was decreased to 1.8 Gy/day. This 10% dose attenuation was su...