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Do you treat prosthetic joint infections after a two-stage revision arthroplasty with oral antibiotics for the full duration of therapy, assuming a susceptible oral option is available?

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What is your approach to using oral antibiotics to treat prosthetic joint infections after a two-stage revision arthroplasty, assuming a susceptible oral option is available?

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2 Answers
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Infectious Disease · Hurley Medical Center
Answered on

This is a hard one-I definitely think the data is there for PO, but until the IDSA recommendations change and the culture of practice changes it is hard to make the switch to doing a full regimen PO! I also think the accountability of IV antibiotics is useful -with the visiting nurse, weekly labs, i...

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Infectious Disease · University of Minnesota Medical School, Minneapolis, Minnesota, United States
Answered on

There is strong evidence supporting oral therapy, particularly from the landmark OVIVA trial. About 16% of participants in this trial fit this profile. It's important to note that most participants transitioned to oral therapy after 7 days. However, it's unclear whether transitioning after fewer day...

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