Mednet Logo
HomePrimary CareQuestion

Do you treat prosthetic joint infections after a two-stage revision arthroplasty with oral antibiotics for the full duration of therapy, assuming a susceptible oral option is available?

2
2 Answers
Mednet Member
Mednet Member
Infectious Disease · Hurley Medical Center

This is a hard one-I definitely think the data is there for PO, but until the IDSA recommendations change and the culture of practice changes it is hard to make the switch to doing a full regimen PO! I also think the accountability of IV antibiotics is useful -with the visiting nurse, weekly labs, i...

Register or Sign In to see full answer

Mednet Member
Mednet Member
Infectious Disease · University of Minnesota Medical School, Minneapolis, Minnesota, United States

There is strong evidence supporting oral therapy, particularly from the landmark OVIVA trial. About 16% of participants in this trial fit this profile. It's important to note that most participants transitioned to oral therapy after 7 days. However, it's unclear whether transitioning after fewer day...

Register or Sign In to see full answer