Does a high genomic risk score impact your radiation fields for patients with breast cancer?

Agree with @Dr. First Last.

In SLN-negative situations with high scores, I would favor whole breast (rather than PBI). High genomic risk scores have been correlated with increased LRR.

Elegant summary recently presented by @Dr. First Last,

ASTRO – Session EDU23.

There aren't prospective randomized data to support this, but I do use Oncotype to help me decide when to apply EORTC 22922 to offer RNI for medial, node-negative cancers. Although the trial was negative for its primary endpoint of overall survival, I a) find the absolute reduction in breast cancer ...

For SLN-positive patients, if the high genomic score favors RNI instead of high tangent.