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For borderline resectable pancreas treated with induction chemo therapy and minimal radiographic response, if unable to do SBRT, do you prefer 36/15 or 50.4/28 (given that is where we have more data)?

The concern being that if patient does not go to surgery, you have delivered lower BED with 36/15.
1 Answer
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Radiation Oncology · Memorial Sloan-Kettering Cancer Center
Answered on

Low dose small-volume SBRT should not be used in the preoperative setting for pancreatic cancer. It was never a good idea to begin with. Due to very tight margins of 2-5 mm on the GTV, it has resulted in 30-50% marginal miss resulting in local recurrences outside of the treated volume now reported i...

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