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For Hodgkin lymphoma patients with initial splenic involvement, do you ever include the pre-chemotherapy involved spleen as part of your consolidative ISRT treatment after a CR?

If the patient had a CR by PET/CT after 2 cycles of ABVD and received 6 cycles of ABVD would you recommended consolidating only the bulky disease and avoid radiating the splenic disease?
2 Answers
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Radiation Oncology · Duke University Medical Center
Answered on

Our long standing policy, first at Yale, for the last 3 decades at Duke, has been to use consolidation RT to all sites of disease known to be present prior to chemotherapy, irrespective of "bulk". On a log scale little difference between bulk and clinically detectable disease of any size. The origin...

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Mednet Member
Mednet MemberInvited Expert
Radiation Oncology · Duke University Medical Center
Answered on

Whether to treat above and below diaphragm at the same time depends on the exact areas being treated. If both fields are relatively small, it is OK. in the past when treating a mantle and paraaortic nodes and spleen for example they were done separately with a gap of about 3 weeks to allow for marro...

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