Given results of the RADICALS trials, is LT-ADT standard of care for salvage prostate RT?
I do not think long-term ADT is established as standard of care for salvage prostate radiation, as this would require a demonstration of improved overall survival in at least specific subgroups of patients. RADICALS-HD demonstrates improvement in freedom from metastasis as well as freedom from non-p...
I don’t think I could add much to Dr. @Dr. First Last and Dr. @Dr. First Last comprehensive analyses. However, since I was asked for an update, I thought the addition of a paper that has been published since the filing of those responses may be helpful.
DADSPORT (Burdett et al., PMID 40571441) was a ...
One important thing to note about RADICALS-HD is that the distribution of patients in the different comparison arms is not uniform.
This has to do with the fact that physicians were able to advise and let the patients choose which randomization they would prefer. We can safely assume that physicians ...