Have you used topical rapamycin/sirolimus for TSC-related angiofibromas?

I used it before it was approved for the treatment of vascular lesions and noted that it was effective and safe.

I have used it in 4 patients, and it is more effective over ablative laser treatment of lesions or fractional ablative laser for better drug delivery.

It works well and is very safe.

Studies with topical sirolimus demonstrate the safe and effective use of the agent for treatment of TSC-related angiofibromas.