How do you approach evaluation for underlying rheumatologic disease in patients with chronic asymptomatic thrombocytopenia?
Thrombocytopenia is moderate (80-100,000 microL). No concomitant cytopenias present.
Answer from: at Academic Institution
APL testing as well as evaluation for SLE and Sjogrens with complement, urine, antibody testing, not just an ANA.
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Answer from: at Community Practice
Agree with Dr. @Cuoghi Edens.
Of course, don't forget about the DDX for drug effect, pseudothrombocytopenia from clumping, infections (like hep C), liver dz, etc etc etc.
But focusing on ruling out autoimmune disorders, adding a few Pearls:
On PE look for painless oral ulcers on the palate, disco...