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How do you approach locally advanced gastric cancer with no pathologic treatment response to preoperative chemo?
Do you recommend changing the chemotherapy regimen post-operatively? Do you recommend post-operative chemoradiation?
Answer from: Radiation Oncologist at Academic Institution
The prognosis in patients who have not responded to preoperative chemotherapy is relatively poor. It does not seem that more cycles of the same chemotherapy are an appropriate strategy- would likely produce more toxicity than benefit. There are some data suggesting that switching chemotherapy regime...
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