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How do you approach systemic treatment for intracranial only brain metastases for ER positive, PR negative, HER2 negative breast cancer after stereotactic radiosurgery for brain metastases with negative PET imaging?
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Mednet Member
Medical Oncology · H Lee Moffitt Cancer Center, University of South Florida
Assuming the patient's treatment history doesn't suggest resistance, I would treat the patient with endocrine therapy plus abemaciclib along with regular brain MRI monitoring.