How do you approach systemic treatment for intracranial only brain metastases for ER positive, PR negative, HER2 negative breast cancer after stereotactic radiosurgery for brain metastases with negative PET imaging?

1 Answers

Mednet Member

Medical Oncology · H Lee Moffitt Cancer Center, University of South Florida

Assuming the patient's treatment history doesn't suggest resistance, I would treat the patient with endocrine therapy plus abemaciclib along with regular brain MRI monitoring.

How do you approach systemic treatment for intracranial only brain metastases for ER positive, PR negative, HER2 negative breast cancer after stereotactic radiosurgery for brain metastases with negative PET imaging? | Mednet