How do you approach the treatment of de novo, brain only metastatic HER2 positive breast cancer?

Topics: Breast Cancer • Medical Oncology • NCI-CCC Tumor Board Question • Her2+ • Moffitt Cancer Center • NCI-CCC Breast Tumor Board Question • CNS Disease • Breast Cancer, Metastatic

Answer from: Medical Oncologist at Academic Institution

Patients who present with de novo, brain-only metastases of HER2+ breast cancer are rare, and hence, there is no good clinical experience or clinical trial basis upon which to base clinical practice recommendations. The current ASCO guidelines for the management of HER2+ brain metastases call for ap...

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