How do you approach the use of chronic azithromycin in patients with CF who may require therapy with IV tobramycin in the future?

Topics: Pulmonology • Cystic Fibrosis

Given the suggestion of the antagonistic effect of azithromycin on IV tobramycin in prior studies.

Answer from: at Academic Institution

This question has been somewhat analyzed in the TEACH study comparing coadministration of azithromycin and inhaled tobramycin. The authors found no difference in lung function but higher pseudomonas CFU reduction in patients treated with inhaled tobramycin alone. In the situation of IV tobramycin fo...

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at Hospital of the University of Pennsylvania
I agree with @Marty; the only reason to stop would...

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