How do you assess the potential role of obesity in driving inflammatory joint symptoms?
Can obesity alone, independent of other comorbidities like psoriasis or presence of ACPA, act as a primary etiological factor in the development of inflammatory arthritis or spondyloarthritis?
Answer from: at Academic Institution
Unlike psoriatic arthritis, obesity has not been observed to be a primary etiological factor in the pathogenesis of RA.Metabolic syndrome is not a risk factor for the development of RA.However, the data supporting a role for obesity as a driver of ongoing inflammation in patients with RA is mixed. O...