How do you assess the potential role of obesity in driving inflammatory joint symptoms?

Unlike psoriatic arthritis, obesity has not been observed to be a primary etiological factor in the pathogenesis of RA. Metabolic syndrome is not a risk factor for the development of RA.

However, the data supporting a role for obesity as a driver of ongoing inflammation in patients with RA is mixed....

I don’t find that obesity has much of a link to inflammatory arthritis. We have numerous studies that our medications are more efficacious in PsA patients, specifically, the TNF works better, and numerous studies that weight loss overall lessens disease activity in known and confirmed inflammatory a...