Do you think we can extrapolate the results of TOGETHER-PsA and expect similar results and safety when adding Tirzepatide to another IL-17 inhibitor or to a bDMARD with different mechanism of action?
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What barriers are currently limiting your incorporation of tirzepatide into the care of your patients with PsA?
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2 Answers
Mednet MemberInvited Expert
Rheumatology · University of Rochester
Answered on
Yes and no. We don't have hard randomized controlled trial (RCT) data with biologic disease-modifying antirheumatic drugs (bDMARDs) other than ixekizumab at present. However, if we extrapolate data from prior weight loss studies in psoriatic arthritis (PsA) and psoriasis (PsO), it would be reasonabl...
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Mednet MemberInvited Expert
Rheumatology · University of Rochester Medical Center
Answered on
Yes. An abstract presented at the recent EULAR meeting showed the efficacy and safety of GLP-1 agents in combination with other biologics, using a propensity-matched retrospective control group (Venerito et al., EULAR 2026).
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