How do you contour and dose definitive CRT target volumes for an unresectable NSCLC invading vertebral bodies?

This is both an excellent and a complicated question.

While I do not typically favor elective nodal radiation in NSCLC, I do think this is a case where some degree of elective coverage is warranted.

Different imaging modalities yield very different contours when it comes to bone invasion in NSCLC, a...

While I agree with @Dr. First Last' thoughtful approach (in particular, always using spinal MRI to define the degree of invasion), I would allow a maximum spinal cord dose to reach 54 Gy in view of the potential devastating impact of any local failure, such as cord compression. In my mind, this is a...