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How do you counsel patients who are candidates for a clinical trial regarding their options?

Specifically, are there strategies you use to 1) empower patients to participate in decision-making and 2) reassure patients who may be skeptical?
2 Answers
Mednet MemberInvited Expert
Gynecologic Oncology · Virginia Commonwealth University Health System
Answered on

I typically discuss the option with patients as early as possible in their diagnosis, and explain that at some point during their treatment they may become a candidate for a clinical trial. I discuss resources to look into clinical trials and what they mean for patients. We discuss patient website resources for NRG, ASCO, etc. We discuss specific advantages clinical trial patients have including a dedicated staff, things like central review, the benefit to future patients, and the idea that thei...

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Mednet MemberInvited Expert
Medical Oncology · Yale School of Medicine
Answered on

I agree with Dr. @Dr. First Last's comments.

In addition, for patients with metastatic disease, I tell them that each time we need to make a change of therapy we will discuss standard options and clinical trial options. I also take time to explain the clinical trial life cycle of Phase I, II, and III clinical trials and the basic goals of each (safety for Phase I, early efficacy for Ph II, and confirmed efficacy for Ph III, and that a treatment is better than a SOC). I make it very clear that no...

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