How do you define bulky disease for Hodgkin's lymphoma which is outside the mediastinum?
Do you use a cutoff of 10 cm? Do you measure the size of the largest node or measure the largest conglomerate or measure the total length of the entire involved chain (i.e. in a patient that has numerous involved nodes extending from axilla up to supraclavicular region)?
1 Answer
Mednet MemberInvited Expert
Radiation Oncology · University Hospital Basel
Answered on
Definition of bulk in lymphoma is not homogenous among countries, study groups, and diseases.
Overall, 10 cm is considered the cutoff by some. Recently, the cutoffs of 7 or 7.5 cm have been introduced, especially in DLBCL.
The definition tends to be disease-specific sometimes, since landmark studies ...
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