Is it necessary to prescribe a steroid taper after two weeks of high-dose prednisone (60 mg daily)?
Answer from: at Academic Institution
Interesting question. Not being an endocrinologist, I don't have the expertise to advise but the reference below makes the statement that even short-term steroids can be an issue. I suspect that if you have to stop abruptly from 60 mg daily for 2 weeks, it would probably be fine in most instances bu...
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at Hartford Health Care You might not have to but I think some of if not m...
The simple answer to this is "no" but I think for a bigger picture of when to taper and how to taper, here is a recent link by Brett et al., NEJM Journal Watch 2024.
Of course, I agree with my colleagues.
But... for excellent reviews I must add the most recent open-access European Society of Endocrinology and Endocrine Society Joint Clinical Guidelines for Diagnosis and therapy of glucocorticoid-induced adrenal insufficiency by Beuschlein et al., PMID 3871...
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A very nice flowchart is in the article: The gluco...
at Uniformed Services University of the Health Sciences (USUHS) Excellent, easy, and very practical. Thanks Dr. @K...
My 2 cents: Granted I take care of AYA cancer patients who are otherwise healthy.
I see a lot of high-dose steroid use/recommendations with long tapers for treating immune-related side effects from CPI drugs.
Besides the many side effects we are all aware of, steroids are associated with early rel...
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at Uniformed Services University of the Health Sciences (USUHS) Dr. @Paul Kent: thanks so much! This is very impor...
at FibroFighters Foundation Oops - that is my mistake! I thought we were talki...
at Uniformed Services University of the Health Sciences (USUHS) @Paul Kent: You are good and you gave us some grea...
I have appreciated the helpful responses to the question. One question I cant seem to find an answer to with all the great resources cited is how long does it take to suppress the HPA axis? I suspect it might be based on dose and formulation of CS. I have used the data from years ago that suggested ...
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at UTMB Health I am not an endocrinologist either but my training...
You might not have to but I think some of if not m...